PE Mouse Anti-Human CD110 Antibody (S-3014)
SKU: 55807805054

PE Mouse Anti-Human CD110 Antibody (S-3014)

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Description

PE Mouse Anti-Human CD110 Antibody (S-3014)Product Specification Host Mouse Antigen CD110 Synonyms Thrombopoietin receptor; TPO R; Myeloproliferative leukemia protein; Proto oncogene c Mpl; TPOR; MPL Location Cell membrane Accession P40238 Clone Number S 3014 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Positive Sample human peripheral blood cells Purification Protein A Concentration 0. 2 mg ml Conjugation PE Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3%

Product Specification


Host Mouse
Antigen CD110
Synonyms Thrombopoietin receptor; TPO-R; Myeloproliferative leukemia protein; Proto-oncogene c-Mpl; TPOR; MPL
Location Cell membrane
Accession P40238
Clone Number S-3014
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Positive Sample human peripheral blood cells
Purification Protein A
Concentration 0.2 mg/ml
Conjugation PE
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD110, also known as thrombopoietin receptor (TPOR) or MPL (myeloproliferative leukemia protein), is a 635-amino-acid, single-pass type I transmembrane glycoprotein belonging to the hematopoietic cytokine receptor superfamily, whose extracellular N-terminal region binds thrombopoietin (TPO) with high affinity to activate JAK2/STAT, MAPK and PI3K-AKT signaling cascades that drive megakaryocyte proliferation, differentiation and platelet production, while its cytoplasmic C-terminal tail contains critical motifs for internalization and negative feedback regulation; physiologically expressed on hematopoietic stem cells, megakaryocytes, platelets and endothelial cells, CD110 is essential for steady-state and stress hematopoiesis, and genetic alterations—such as MPL W515L/K activating mutations or CALR exon 9 mutations that create neomorphic ligand binding—lead to ligand-independent signaling, constitutive activation and the development of myeloproliferative neoplasms, making CD110 a key diagnostic marker and therapeutic target for small-molecule JAK inhibitors and TPO receptor agonists/antagonists in thrombocytopenias and myelofibrosis.

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SKU: 55807805054

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Sea Lover
Charlottesville, US
★★★★★ 5
Should serve you well for years.
Color: Silver, Color: Silver
This classy evening bag by CHUNLI is large enough to hold all you will need for an evening out. It will hold your keys, driver's license, money, small brush or comb, lipstick, and of course your cell phone. The clasp on top is a little work of art and yet it still does a great job of holding the bag shut. The silver chain (not copper colored as shown in my photo) is strong and attractive and is easy to attach and remove. It makes the bag hands-free if you choose not to carry it as a clutch. Unlike some evening bags, this is a solid formed shape, and will not warp as a soft bag could do. This will enhance your dressy outfit.
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Reviewed in the United States on April 30, 2026
A
Amber
Houston, US
★★★★★ 3
Cute but Too Hard & Noisy
Color: Nude
I was hoping this would be a little softer, but it’s definitely a hard shell. It is cute, but I don’t think I’d want to take it out much. It also makes a pretty loud noise when you set it down, which is a bit off-putting. Overall, just okay for me.
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Reviewed in the United States on April 12, 2026
W
What I Found
Bozeman, US
★★★★★ 4
Great value for the money with a leveled up intentional design
Color: Black, Color: Black
This clutch is more stylish and elevated than I expected when I ordered it. The overall shape and that wave-like exterior give it a more interesting, elegant look in hand. It comes with a gold chain strap, which is honestly pretty cheap and shiny, but it’s detachable, so you’re not stuck with it. Given the weight and width of the bag, I actually think using a chain makes sense — it’s not the easiest thing to hold comfortably as a clutch for long periods. If I were going to use it regularly, I’d probably swap the chain out for something a little higher quality. The clasp is a gold flower with a small decorative jewel in the center, which adds a bit of personality and makes it feel less generic. That said, the hinge along the bottom is fully visible and would look more refined if it were finished in black or gold instead of standing out. Inside, it’s lined with a satin-like nylon material. There’s elastic on both sides that helps pull the clutch closed, which is a practical detail. It fits a large phone easily, along with the usual evening essentials. It is heavier than expected because of the metal frame, and the exterior is PU (vegan leather), so you get that structured feel. The size is also a bit larger than I anticipated. One thing to note — it doesn’t come with a dust bag or protective cover, and the surface could easily show marks if you’re not careful, so you’ll want to store it thoughtfully. The brand name (CHUNLI) is a bit different, but the design itself does a good job of elevating above that. It’s not perfect — the chain and hinge could be improved — but visually it’s interesting and feels more elevated than the price would suggest.
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Reviewed in the United States on March 28, 2026
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Next Speedy Bubble
New York, US
★★★★★ 5
Excellent Party Purse
Color: Nude, Color: Nude
This is my new favorite clutch. I bought it in Nude and it looks so elegant. As can be seen in the pictures, it is very spacious. I was able to fit a phone, a small wallet and some cosmetics without any issues, and there is still room for more. I also had no issues with the open/close mechanism, which tends to be a problem with some other brands. The chain strap is removable making it a versatile piece. The chain is not adjustable. The exterior material quality as well as the inner lining seems sturdy. The only thing I was not thrilled about is the gold color of the chain and the hook. I wish it was a milder tone of gold or even rose gold. Not taking any star off since it matches the listing.
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Reviewed in the United States on April 14, 2026
A
Ashley
Houston, US
★★★★★ 5
Beautiful gold hard shell clutch
Color: Gold, Color: Gold
I love this elegant hard-shell gold clutch. It comes with a chain that is easy to clip on if you prefer to wear it as a purse. It fits my phone, keys, and cards (or a small thin wallet) and even has an inside pocket. The push-to-open flower clip on top is beautiful and makes it very easy to access. The flower detail is stunning and adds a touch of glamour. This clutch is perfect for any formal night or even a casual date night.
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Reviewed in the United States on April 13, 2026

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